Clinical Backgrounds in Cases of Gastric Cancer Diagnosed by Gastroendoscopy in Ningen Dock

Abstract

Objective: We evaluated the clinical backgrounds of examinees diagnosed with gastric cancer by gastroendoscopy in our Ningen Dock.
Methods: A total of 20,051 persons examined by gastroendoscopy in Ningen Dock were enrolled in this study. They were classified into groups based on the interval between the previous gastroendoscopic examination and the current one, into an annual group, a non-annual group, and a first-time group. In addition, they were classified by atrophy of gastric mucosa into 5 categories; none, slight, moderate, severe, and unknown.
Results: Incidence of gastric cancer: A total of 52 cases (0.26%), 48 (0.34%) in males and 4 (0.07%) in females, were diagnosed by gastroendoscopy, with 30 (0.21%) in the annual and non-annual groups and 22 (0.38%) in the first-time group. Relationship between history of gastroendoscopy and size and depth of cancer: The incidence of a size of less than 20 mm was 73.7% (14/19) in the annual group and 36.4% (8/22) in the first-time group. Regarding incidence of musosal cancer, such cancer was present in all of 16 subject in the annual the group and 59.1% (13/22) in the first-time group. Relationship between atrophy of gastric mucosa and histological type: Well-differentiated carcinomas were detected more frequently in stomachs with atrophic mucosa. Three cases without atrophy of gastric mucosa had signet-ring cell carcinomas and were negative for anti-Helicobacter pylori antibodies.
Conclusions: Annual examination by gastroendoscopy is useful for the early detection of gastric cancer.