Abstract
Objective: It has been shown that Helicobacter pylori infection is a critical risk factor for gastric cancer. This study was conducted to clarify the usefulness of gastro fluoroscopy for the diagnosis of Helicobacter pylori infection.
Methods: We investigated 200 examinees (118 males, 82 females) who visited our health care center for health check-ups between April, 2011 and March, 2012. We evaluated the usefulness of gastro fluoroscopy for the diagnosis of Helicobacter pylori infection by comparing gastro fluoroscopy images with serum Helicobacter pylori antibody titers. We considered that subjects had Helicobacter pylori infection when a diagnosis of atrophic gastritis was made on the basis of f gastro fluoroscopy images.
Results: Chronic gastritis (including atrophic gastritis) was observed in 96.8% of subjects who were serum Helicobacter pylori antibody positive. Chronic gastritis was noted in 100% of subjects both serum Helicobacter pylori antibody positive and pepsinogen positive. On the other hand, chronic gastritis was observed only in 10.6% of subjects both serum Helicobacter pylori antibody negative and pepsinogen negative. Thus, on the basis of gastro fluoroscopy, diagnosis of Helicobacter pylori infection had a sensitivity of 91.5%, specificity of 93.3% and an accuracy of 92.3%.
Conclusions: Our results suggest that gastro fluoroscopy is a useful tool for the diagnosis of Helicobacter pylori infection.
