2020 Volume 35 Issue 4 Pages 612-619
Objective: The present study aimed to evaluate the usefulness and challenges of propofol (pf) sedation for esophagogastroduodenoscopy (EGD) in a comprehensive health check-up system (CHCS).
Materials and Methods: The subjects were 8,889 patients who received CHCS in our hospital between 2014 and 2019. The subjects chose between EGD or barium meal radiography for examination of the upper gastrointestinal tract. Furthermore, they decided to undergo EGD with or without pf sedation. A bolus dose (0.8–1.2mg/kg) of pf was injected intravenously just prior to EGD. SpO2 and pulse were monitored in patients who underwent EGD with pf sedation. Medical records detailed the adverse effects. The sentiments of the subjects who underwent EGD with pf sedation were studied in 600 patients with a satisfactory investigation. An interview was conducted to collect their opinions on the topic.
Results: The number of patients who received CHCS had increased annually, and in 2018, it increased to approximately 1.4 times that in 2014. The patients who underwent EGD with or without pf sedation also increased. Adverse effects, such as respiratory suppression (3.25%), unconscious body movement (0.81%), and emergence delay (0.56%), were seen among patients who underwent EGD with pf sedation. However, no severe complications developed except bronchial convulsion in one case. Patients who underwent EGD with pf sedation stated their positive opinions in the interview. Most negative opinions could be attributed to their increased workload.
Conclusions: Introduction of EGD with pf sedation may increase the number of patients who receive CHCS. However, awareness of the harmful effects and increase in medical staff may be necessary to improve safety of the n the future.
