Abstract
Objective: We evaluated qualitative coronary artery calcification (CAC) by visual assessment and the significance of risk factors in human dock lung cancer CT screening.
Methods: The subjects consisted of 184 people who underwent lung cancer CT screening from April 2019 to March 2020 (average age 60±9 years, male 172, female 12). A visual qualitative evaluation of CAC was performed in chest CT cases for a lung cancer work-up. Chest CT was performed with a 16-row multi-slice CT (HITACHI, Supria®), with non-gated non-contrast acquisitions, and 5-mm slice thickness. Those in which there were two or more slices of calcification in the main coronary artery region were classified as being ＂moderately positive＂ We examined the presence or absence of CAC, health check-up items, and Framingham score.
Results: In 184 cases, there were 30 cases (16.3%) with moderately positive CAC. The mean age was 65.7±5.3 (range, 55–77 years), and the frequency was higher in men (90%). Logistic regression analysis of health check-up items related to CAC with 78 cases with age-matched no calcification group showed Age (≥70), BMI (≥25), diabetes, LDL cholesterol (≥180 mg/dL), and 12-lead ECG abnormality. The Framingham score was significantly higher in the CAC group (10.0±4.2 vs. 6.9±2.9, p<0.01).
Conclusion: CAC by visual qualification on lung cancer CT screening with non-gated and non-contrast acquisitions was associated with lifestyle-related diseases and was a useful method of assessing the risk of coronary artery disease in human docks.
