2022 Volume 37 Issue 4 Pages 684-692
Objective: The objective of this study was to examine the significance of measuring serum 25(OH) vitamin D concentration at Ningen Dock.
Methods: We examined the relationships between 25(OH)D and bone mineral density, age, BMI, nutrition, renal function, bone metabolism, and glucose metabolism in 1,333 subjects whose serum 25(OH) vitamin D (25(OH)D) was measured during the year from April 2021 at our clinic’s Ningen Dock.
Results: Vitamin D deficiency (serum 25(OH)D: <20 ng/mL) and insufficiency (≥20 and <30 ng/mL) were common in both sexes and were found in 82% of all subjects. Multiple regression analysis showed that 25(OH)D and Cr were factors that increased bone mineral density in women <50 years. In addition, 25(OH)D was significantly lower in the group with abnormal glucose metabolism (HbA1c≥5.6%) than in subjects with normal levels. In addition, the number of cases with abnormal glucose metabolism were higher in those aged ≥50 years, and HbA1c was one of the factors for decreasing bone mineral density in male ≥ 50 years.
Conclusion: The overall frequency of vitamin D deficiency/insufficiency was high, at more than 80%. At Ningen Dock, it may be worthwhile to measure 25(OH)D in women <50 years and to provide dietary and sun exposure guidance in patients with deficiencies. Future studies on the relationships among abnormal glucose metabolism, 25(OH)D, and bone mineral density are warranted.
