Abstract
Life-style diseases induced by excessive caloric intake, a shortage of exercise, stress, alcohol and smoking, tend to increase from the younger generation and to complicate some risk factors which provoke atherosclerotic cardiovascular disease in some cases. So, we studied the relation between fatty liver and the Deadly Quartet (obesity, hyperlipidemia, glucose intolerance, hypertention) at the outpatients(from 18 to 77 years old,707 men,184women, total amounts 991). The patients diagnosed as fatty liver showed a tendency of (1)obesity (2) hypertriglyceridemia, hypercholesterolemia and decreased HDL cholesterol (3)glucose intolerance (4) severe hypertension (5) hyperuricemia. The coincident rates of the Deadly Quartet were four; 7 patients (2.5%), three; 25 (8.9%), two; 77 (27.3%), one; 139(49.3%) and nothing; 34 (12.1%). On the other hand, in the cases of the patients diagnosed as non-fatty liver were four; 0, three; 12 patients (1.7%), two; 67(9.4%), one; 357 (50.4%)and nothing; 273 (38.5%). So, the state of fatty liver should be regarded as the early stage of life-style diseases and as one of the risk factors. We suggest that fatty liver, obesity, lipid dysbolism, glucose intolerance and hypertention at the medical check were the negative factors to live healthy and happy. With the increment of the number of the risk factors, the incidence rate of life-style diseases and atherosclerotic cardiovascular disease increase. Then, in the case of non-alcoholic fatty liver, it is possible to be NASH (nonalcoholic steatohepatitis) and advance to serious state.
