Abstract
Background and Methods The urine protein/urine creatinine (P/C) ratio measured by fully automatic equipment was compared with the urine albumin excretion index (AEI), and pathophysiological changes in dissociation cases of urine P/C ratio and AEI were determined.
Results The quantitative value of the P/C ratio was significantly correlated with that measured by Clinitek® ATLAS XL. Dissociation between the urine P/C ratio and AEI was observed in cases of hypertension, hyperlipidemia, and hypoalbuminemia, and they were complicated by cerebral infarction and heart disease.
Conclusions These results suggest that atherosclerosis plays a role in the pathogenesis of the dissociation. Also, the urine P/C ratio being higher than the AEI suggests that globulin was excreted more than albumin under pathological conditions. In conclusion, the urine P/C ratio may be used to detect pathological conditions which might not be detected by AEI, and thus, measurement of the P/C ratio with the AEI may be more useful.
