Abstract
Objective: We reevaluate the waist circumference in the diagnostic criteria of metabolic syndrome in Japanese. Methods: We enrolled 3,332 subjects (1,921 men and 1,411 women)who consulted annual health check-up and Ningen dock in our center. The criteria were reevaluated by the receiver-operating characteristics (ROC) curve according to the accumulation of any two of the following three abnormalities: blood pressure, lipid level, and blood glucose level. In order to draw ROC curve, we hypothesized 10 different points of waist circumference from 72cm to 95cm, and calculated both sensitivity and specificity. We determined the most ideal waist circumference from the cut-off point of the ROC curve. We also drew ROC curves according to atherosclerotic findings based on eye fundus photograph, electrocardiogram, brain magnetic resonance image and magnetic resonance angiography, and echogram of the common carotid artery. Based on the newly detected waist circumference, we compared the pseudo-negative ratio of the atherosclerotic findings in the participants who were diagnosed as metabolic syndrome by the present criteria. Results: The ideal waist circumference was hypothesized as 85cm in men and 80cm in women. This new proposed waist circumference decreased the pseudo-negative ratio of metabolic syndrome in women. Conclusion: By using a new waist circumference proposed in this study, the diagnostic probability of metabolic syndrome in Japanese women is improved.
