Dermatochalasis; A Case Report of Generalized Elastolysis

Abstract

The diffuse elastic tissue disease called dermatochalasis, although very rare, are reported ten cases in Japan. One of these case, a 35 year old house wife, in this disease died and came to autopsy. Extensive histologic studies on skin and other organs demonstrated a defect of elastic fibers throughout the body. Histologic examination of the involved skin reveals swollen and irregulaly clumped of elastic fibers and calcium imbibition. The change of aortic wall, pulmonary emphysema and prolapse uteri were present.