Abstract
Patch-testing of the corticoid preparations on psoriatic lesions was performed as a new device to evaluate the therapeutic effect of topical corticoid preparations. Effects of the concentration of clobetasol 17-propionate upon the improvement of psoriatic lesions were investigated in 7 patients. The concentrations of the drug employed were at 0.1%, 0.05%, 0.025% and vehicle alone in cream and ointment base, respectively. It was found that the 0.05 % clobetasol 17-propionate preparations possessed a sufficient therapeutic effect in the both vehicles. The preparations are found more effective on psoriatic lesions than the other commercial corticoid preparations.
