Abstract
A 51-year-old woman suffering from common cold was treated by a physician. About ten hours after medication she felt feverish with elevated body temperature of 38.5°C and immediately after multiple erythema took place on whole body surface. At the admission to the Nagasaki City Hospital, peripheral blood was examined without any abnormal finding except for elevated serum transaminase value (GOT 240 and GPT 88), but six days after admission agranulocytosis (no stab and segmented) developed. The causative drug was supposed to be sulpyrin by patch testing and lymphocyte blastotransformation using the drugs as antigens.
