Abstract
Responses of basophilic and eosinophilic leucocytes in the skin window applied to skin reactions of PHA, PWM and LPS as well as to PPD were investigated with the following results: 1) At 8 and 24 hours after the intracutaneous injection of each mitogen, PHA, PWM and LPS, as well as of PPD, basophilic leucocytes were observed by the skin window technique, which indicated that each of the skin reactions with these mitogens may represent the delayed type of hypersensitivity as the PPD reaction does; 2) At 2, 8 and 24 hours after the intracutaneou injection of each mitogen and PPD, eosinophilic leucocytes were also observed by the skin window tachnique; 3) A comparative study on the response patterns of basophilic and eosinophilic leucocytes in the skin windows between each of the three mitogens and PPD revealed that the pattern by PHA, by PWM and by LPS resembled that by PPD in this order.
