Statistical Studies on Drug Eruptions, Contact Dermatitis and Melanosis Faciei Feminae

—III. Melanosis Faciei Feminae—

Abstract

By clinical and statistical analyses of the patients of melanosis faciei feminae observed at the dermatological clinic of Yamaguchi University Hospital for 10 years, from 1964 to 1973, the following results were obtained: 1) the outpatients observed in this period were 29,440 in number and comprised 191 cases of melanosis faciei feminae (0.6%); 2) the number of cases as well as the incidence rates of this disease per year showed a small peak at 1966 and a higher peak at 1972; 3) the number of cases per month was large in May, April, June, March and October in the order of decreasing frequency, and small in November and December; 4) the cases as well as the incidence rates of this disease at the age decade were found positively from the third decade, and increased in number rapidly at the fourth decade, reaching the highest peak at the fifth decade; 5) of 39 patients who had been tested by patching various cosmetics, 25 cases (64.1%) were positive; 6) make-up cosmetics were mostly patch-tested and creams, beauty washes and cosmetic emulsions followed them in the order of decreasing frequency, and cosmetic emulsions, make-up cosmetics, beauty washes and creams were most frequently found positive by patch testing in the order of decreasing frequency.