Abstract
A 29-year-old female visited Nagasaki University Hospital Dermatology Clinic because of discoloration of her right thumb nail. The distal part of the nail plate was slightly thickened and onycholytic with dark-brown pigmentation. There was no paronychia. Removal of the onycholytic nail plate revealed brittle subungual hyperkeratosis. Round fungus spores or pseudomycelia compatible with parasitic form of yeasts were seen by KOH-preparation and also by Gomori’s methenamine silver stain, and Candida parapsilosis was isolated. The patient was treated with topical use of 5% glutaraldehyde solution but the course was not continued.