Abstract
Intradermal skin tests and in vitro antigen-induced histamine release from leukocytes were carried out using mite, house dust and several fungal allergens in chronic urticarial patients who had no other atopic diseases. The causes were not identifiable from the history in the patients. Seventy-two out of 106 cases (67.9%) gave positive skin tests with at least one of the allergens used in the present experiments. The results of the skin tests suggest that mite, house dust and Candida allergens may be important allergen in chronic urticaria. These were supported by the results of the antigen-induced histamine release from leukocytes of the chronic urticarial patients.
