Abstract
A clinical study was done on methods available for estimating the antitumor resistance in patients with malignant skin tumors. Fifteen parameters were used to assess 55 cases. As the immunological parameters, the counts of lymphocyte and T-cell, PHA stimulated lymphoblastgenetic index and delayed skin reactions of PPD, PHA, candida and SK/SD were used. As for the general conditions, RBC, hemoglobin, albumin, choline esterase. WBC, IgG, weight loss and extent of bed rest were used and followed-up every two weeks after the initiation of the chemotherapy. The results obtained were as follows: 1) The two kinds of parameters showed significantly lower values in the last stage of dead group in comparison with those in the remission stage of survival group, except for the counts of leucocytes and IgG. 2) The total scores, as well as those concerning immunological and general conditions devised for evaluation of the parameters, showed fairly good correlations with the clinical courses in the dead and the survival groups. Thus, these scorings may be used to indicate of cessation or recommencement of chemotherapy in the late stages.
