Abstract
Pearl barley (“hatomugi”) is a Chinese medicine used to treat verruca (warts). In vitro experiments showed that the effect of pearl barley extracts on verruca was more potent when the rind of the seed of the fruit (especially the former) compared with the seed as a whole (“Yokuinin” in Japanese). (See Report I and Report II) After extraction of the contents from the rind with hot water, an injectable solution was obtained from the supernatant and a topical agent, from the sediment. We used these extracts in experiments to determine their usefulness in the treatment of verruca vulgaris and verruca planae. Injections were given intracutaneously in a dose of 0.1 to 0.3 ml once a week, while the topical agent was applied to the lesion several times a day. The results of the application of topical agent on verruca vulgaris and verruca planae were satisfactory. The preparatory method for the topical agent, subjects for treatment, results and related discussion were reported herein.
