Abstract
A 49-year-old woman had diffuse sclerotic cutaneous lesions and a few coin-sized indurated erythematous eruptions on her legs. Laboratory data showed circulating eosinophilia, elevated sedimentation rates and hypergammaglobulinemia. Rheumatoid factor, LE cells, antinuclear antibodies and complement level were negative or normal. Biopsies obtained from skin lesions of her left leg revealed conspicuous thickening of the fascia and infiltrations of lymphocytes, eosinophils, histiocytes and neutrophils in the dermis. Lymphocytic infiltration was also observed in the muscle tissue of the lesion. X-ray of the leg bones showed a hypertrophic change in the periosteum. The patient had a thyroid nodular tumor which histologically proved to be papillary carcinoma.
