Abstract
In a 68-year-old man with unilateral Darier’s disease, a carbuncle appeared on the involved area of his left back. After excision, multiple organ failure, including pulmonary suppuration and edema, renal failure, liver dysfunction, digestive tract bleeding and consciousness disturbance occurred. The Darier’s disease also worsened. The eruption improved somewhat following improvement of his general condition, with intensive care. Immunological abnormality related to infection and the therapy, were discussed.
