Localization on Hemosiderin in Secondary Hemochromatosis

—Electron Microscopic and X-ray Microanalysis Study—

Abstract

An ultrastructural study of secondary hemochromatosis was performed. Small electon-dense particles were observed in eccrine sweat gland cells and dermal macrophages but not in epidermal keratinocytes or in vascular endothelial cells. In the eccrine gland, these particles located at the luminal side of each cell, but not in the thick lamina densa. They contained iron as determined by energy dispersive X-ray microanalysis.