Intraperitoneal Cisplatinum Chemotherapy in Patients with Peritoneal Metastatic Melanoma

Abstract

In a 65-year-old man with stage IV malignant melanoma, metastatic skin lesions were treated with intralesional infusions of γ-interferon and interleukin-2. However, no response was seen. Chemotherapy for carcinomatous peritonitis with a combination of intraperitoneal injections of cisplatinum and intravenous injections of vinblastine and dacarbazine caused a reduction of ascites and in the size of metastatic skin lesions.