Abstract
We cultured non-epithelial cells derived from an extra-abdominal desmoid tumor (17-year-old male), and studied the characteristics of the cells, comparing them with normal skin fibroblasts (12-year-old male). (1) Desmoid cells could be subcultured for only about one year, which was shorter than in normal fibroblasts. (2) The shape of cells was the same as that of fibroblasts, but the rate of proliferation was lower than that of the control. (3) The rate of collagen synthesis of desmoid cells was the same as in the control. (4) Fc receptors, the staining of acid phosphatase and esterase, and immunophagocytosis were all negative in desmoid cells. Therefore, the nature of desmoid cells was similar to fibroblasts, and not to “facultative fibroblasts”.
