Acral Lentiginous Melanoma in Situ Arising from Compound Nevus

Abstract

We report a case of acral lentiginous melanoma in situ arising from a pigmented nevus of compound type. After simple resection of a small pigmented fleck on the right sole, recurrence occurred twice on the same site. As the histological examinations during surgery suggested malignant melanoma, a wide-resection and full-thickness skin graft were performed. The pathological specimen showed a picture of advanced stage of acral lentiginous melanoma in situ. After surgery, two courses of chemotherapy with DTIC (100 mg/day for 5 days ×2) were carried out, and no recurrence has been observed during these last 2.5 years.