Malignant Proliferating Trichilemmal Tumor Occurring in the Scar of Tuberculosis Verrucosa Cutis

Abstract

A 68-year-old man had tuberculosis verrucosa cutis on the right lower limb with incomplete treatment for fifty years. He had never received X-ray therapy. The lesion of tuberculosis verrucosa cutis was an atrophic scar surrounded by elevated verrucous dull red plaque. A walnut-sized reddish tumor appeared in the scar and grew rapidly over a three month period. The diagnosis of tuberculosis verrucosa cutis was confirmed on biopsy examination and a histological examination of the tumor revealed a malignant proliferating trichilemmal tumor. The tumor was completely excised and the tuberculosis verrucosa cutis lesion cleared with an oral administration of isoniazid and rifampicin for about half an year. This case is the first report of a malignant proliferating trichilemmal tumor occurring in the scar of tuberculosis verrucosa cutis.