Abstract
We report a case of cutaneous leiomyosarcoma in a 44-year-old Japanese female. The lesion was a brownish plaque of 25×36 mm in size on the left subscapular region and a subcutaneous nodule was palpable underneath. Histopathologically, spindle shaped tumor cells infiltrated from the upper dermis to the subcutaneous fatty tissue in a haphazard manner. Considerable nuclear pleomorphism and atypical mitotic figures were also noted. Electron microscopically, the tumor cells showed a jagged nucleus and few organelles in the cytoplasm. A small amount of thin filaments were noted in the cytoplasm, but a dense body and basement membrane were not conspicuous.