Abstract
A statistical analysis of the clinical features observed in the patients demonstrating positive anticentromere antibody was studied over a 3 year period since 1990 to 1992. Total of 55 patients (male 3 cases; female 52 cases) were detected. Mean age was 56.9±13.8 years old. The clinical diagnoses were as follows, systemic scleroderma; 45 cases (82.0%). SLE; 1 case, DLE; 1 case, morphea; 1 case, psoriasis vulgaris; 2 cases, atopic dermatitis; 1 case, Darier disease; 1 case, polymorphous light eruption; 1 case, prurigo chronica multiformis; 1 case and macular amyloidosis; 1 case, respectively. The serum A/G ratio, pulmonary involvement, esophageal involvement, cardiac involvement and renal involvement were then compared between the Barnett I group and Barnett II/III groups in systemic scleroderma patients. There was no statistical significance in these investigations between the Barnett I group and Barnett II/III groups except for the % DLco in the pulmonary function test (p<0.01).
