Abstract
A case of eruptive xanthoma which developed in a patient with hyperlipidemia and diabetes mellitus was reported. The patient was a 25-year-old Japanese obese male. Laboratory examinations revealed hyperlipidemia and hyperglycemia, diabetes mellitus and proteinuria. The skin rash consisted of numerous red to yellowish papules with a erythematous halo. The histological examination revealed an admixture of foamy cells, lymphoid cells, histiocytes and neutrophils. The foamy cells stained red with oil red O or yellowish red with Sudan III. Systemic treatment with anti-hyperlipidemia and anti-diabetes mellitus agents rapidly improved his hyperlipidemia and hyperglycemia. Thereafter, the skin rash began to flatten as soon as the laboratory data normalized. After 5 months of treatment, all the papules disappeared while only some pigmentation remained.
