Abstract
Five cases of pyoderma gangrenosum: a 37-year-old female with aortitis syndrome, a 32-year-old female with Crohn’s disease, a 52-year-old male with rheumatoid arthritis, and a 57-year-old and 61-year-old males with myelodysplastic syndrome are reported. All patients manifested skin ulcers on their lower extremities, and the skin lesions showed a dramatic response to the systemic treatment with glucocorticoid. Two of these patients developed the skin lesions before the underlying and/or associated diseases were manifested. The activity of the cutaneous lesions showed no relationship to that of the underlying diseases. Traumatic insult was considered to be an etiologically important event in all the above patients.
