Abstract
The case of a 30-year-old man with eosinophilic pustular folliculitis (EPF) is reported. The patient first noticed erythema and pustules on his palms and soles, and was initially diagnosed as either dyshidorotic eczema or pustulosis palmo-plantaris. On admission, pustules on erythematous scaly macules were seen not only on his palms and soles but also on his trunk and extremities. Histo pathologically, intra-epidermal pustules containing many eosinophils were observed. The combined oral administration of indomethacin and minocyclin proved to be effective. We also summarized the 22 cases with EPF treated at our hospital. One of these cases showed a high serum level of androgen. The oral administration of indomethacin proved to be effective in most cases. Indomethacin began to show its efficacy within several days, however, skin lesions were found to recur in most cases after discontinuing the indomethacin administration.
