1997 Volume 59 Issue 4 Pages 531-535
We herein report 3 cases of erythema elevatum diutinum (EED), consisting of 3 females aged 29, 76 and 81 years old. These patients presented with a variety of skin lesions, such as erythema, purpura, ulcers, and pustules, in addition to the clinically typical plaques and nodules of EED. It seems noteworthy that purpura and hemorrhagic blisters of the soles were found in all cases and developed in one case as the initial lesions. Topical corticosteroids improved the skin lesions in one case while the administration of dapson was dramatically effective in the other 2 cases. In two patients with positive rheumatoid factor, Mooren-type corneal ulcers appeared almost concomitantly with the development of EED, thus suggesting a close relation between the cutaneous and ocular lesions. We therefore conclude that some EED patients might show a wider spectrum of skin lesions than those normally seen in typical cases and as a result, a careful examination of the cornea is therefore recommended in such cases.