1998 Volume 60 Issue 2 Pages 169-172
A 53-year-old male patient presented at our out-patient clinic with erythematous piaques on the right ventral femoral region. The eruptions had started with an asymptomatic erythema with a couple of nodules 3 months before he visited our clinic. A skin biopsy specimen showed a diffuse proliferation of atypical lymphoid cells throughout the entire dermis. Immunohistochemically, the lymphoid cells were CD2(+), CD3(+), CD4(+), and CD30(+). The patient was thus diagnosed to have primary cutaneous anaplastic large cell lymphoma (Ki-1 lymphoma) and admitted to our hospital far treatment. The patient was first treated with a resection of the erythematous plaque, however, it unfortunately recurred 6 weeks after the operation. The patient was again admitted and treated with chemotherapy by the VEPA regimen, and in addition, with local electron beam irradiation with a total dose of 80Gy. The patient is presently free from lymphoma lesions. It should be noted that not all so-called primary cutaneous Ki-1 lymphoma are as slowly progressive or self-healing as observed in our present case.
