Abstract
Extramammary Paget’s disease usually occurs in the genital region, but sometimes occurs simultaneously in the axillary or some other areas. Some authors have classified such cases as double, triple or multiple Paget’s disease. Some of these cases have subclinical Paget’s condition in which Paget’s cells were recognized histologically in the clinically normal skin. We treated a 66-year-old man with multiple extramammary Paget’s disease involving the genital and bilateral axillary regions. Although all three lesions showed the histological features of extramammary Paget’s disease, no apparent eruption was seen in the left axillary region. No abnormal laboratory data was observed and there was no evidence of metastasis to any other organs. We excised the lesions in all three regions and half-thickness skin grafting was also performed. Multiple extramammary Paget’s disease appears to be less progressive than solitary extramammary Paget’s disease according to our review of the literature but some cases do have metastasis to the regional lymph nodes. We believe that a radical excision is the best therapy when possible.
