Abstract
A 75-year-old man developed various skin lesions including: red papules, erythema, and lichenificated plaques. The lesions gradually worsened even though he was treated with conventional topical and oral therapy. Laboratory examinations revealed hypereosinophilia, which continued for over 6 months. No specific factors could be found based on the findings of laboratory and imaging analyses. Biopsy specimens of the skin lesions revealed an intense infiltration of eosinophils. These clinical and laboratory findings fulfilled the criteria of hypereosinophilic syndrome. We treated the patient with bath-PUVA therapy. After ten exposures (5.4 J/cm2), the skin lesions almost completely disappeared and the hypereosinophilia symptoms also improved.
