The Nishinihon Journal of Dermatology
Online ISSN : 1880-4047
Print ISSN : 0386-9784
ISSN-L : 0386-9784
Clinical Case Reports
Stevens-Johnson Syndrome in an HIV-1 Carrier
—A Probable Case Related to an OTC Drug—
Hiroyuki TERAMAETakeshi KONOMasamitsu ISHIIShin-ichi NISHIShin-ichi TAGAWAChikako YAMASHITA
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2000 Volume 62 Issue 6 Pages 762-765

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Abstract
A 57-year-old Japanese male presented with erythematous eruptions which had extended over almost his entire body over a 2-day period after taking Dickinin®-Capsule D, an OTC for the common cold. He was admitted to the ICU of our hospital. On the initial examination, erythematous macules with bullae and erosions were found on his trunk, extremities and face. Oral and genital erosions were also observed and therefore a diagnosis of Stevens-Johnson syndrome was made, and steroids were orally and intravenously administered. However, on the day after admission, he was identified to be HIV-1 seropositive, and the lymphocytopenia advanced. The steroid treatment was rapidly tapered and human immunoglobulin was added. HHV-6, 7 DNA was not detected in the cutaneous lesions. As a result, drug induced Stevens-Johnson syndrome was therefore suspected.
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© 2000 by Western Japan Division of JDA
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