2003 Volume 65 Issue 2 Pages 162-164
A 55-year-old man, who kept tropical fish in his home, visited our hospital in January 2001 because of multiple subcutaneous nodular lesions with tenderness that had developed on his right hand and forearm following an injury to his right middle finger. A histological examination of a nodule on his right forearm revealed epithelioid cell granulomas with an abscess formation in the dermis and the subcutaneous tissue. Acid-fast photochromogen was isolated from Ogawa medium incubated at 28°C for 2 weeks. The isolate was identified as Mycobacterium marinum according to both DNA-DNA hybridization and various bacteriological identification tests for atypical mycobacteriosis. The nodular lesions, which had become exacerbated after oral treatment with minocycline, sparfloxacin, ciprofloxacin, and levofloxacin, disappeared after the oral administration of rifampicin, 300mg per day and ethambutol, 750mg per day, for 6 months.
