2007 Volume 69 Issue 5 Pages 547-553
We investigated the efficacy, safety, and usefulness of once-daily application of luliconazole 1% cream (Lulicon® cream 1%) for the treatment of tinea pedis at the Department of Dermatology School of Medicine Fukuoka University Hospital and its affiliated centers. Forty-three patients (25 with interdigital and 18 with vesicular) were included in the analysis. After application of Lulicon® for 4 weeks, rates of improvement in dermatological symptoms were 93.8% and 100% and of mycological efficacy (fungi-negative rate) were 100% and 58.3% for interdigital and vesicular tinea pedis, respectively. The efficacy rates in the overall evaluation, which included assessment of dermatological symptoms and results of mycological testing, were 100% and 58.3% for interdigital and vesicular tinea pedis, respectively. Itching disappeared in 58.8% of all patients within one week. Based on these results, and the absence of adverse drug reactions, luliconazole 1% cream (Lulicon® cream 1%) is considered to be quite effective and useful for the treatment of tinea pedis.
