Abstract
A 66-year-old man had a 30×35 mm non-tender subcutaneous tumor on the occipital region. Findings of light microscopy revealed the nodule to have a cystic construction composed of two types of neoplastic cells: i.e., small, dark epithelial cells that tended to form palisades and to be situated at the peripheries of aggregations of neoplastic cells and large, pale epithelial cells, which tended to be situated within small, dark epithelial cells. On the periphery of the tumor nodule, aggregations of large ovoid cells with eosinophilic cytoplasm were recognized. Results of an immunological study using a panel of antibodies suggested that the tumor nodule was derived from the transitional portion of an eccrine duct and gland while the aggregations of large ovoid cells were derived from an eccrine gland.