Abstract
A 33-year-old woman noticed perniosis on the dorsal part of her hands in the winter of 2008, which disappeared the following Spring without any treatment. She came to our hospital in the Winter of 2009 with erythema on the dorsal part of her hands and swollen fingers. A blood examination revealed positive anti-nuclear antibodies (× 160, homogenous and speckled pattern) with lupus anticoagulant, anticardiolipin β2GP antibody and IgG anticardiolipin antibody. The skin lesion was biopsied and showed no evidence of liquefaction degeneration and vasculitis. A lupus band test was also negative. Since there were no events of deep venous thrombosis, pulmonary embolism, stroke or pregnancy loss, she did not meet the criteria of antiphospholipid antibody syndrome (APS). She had no evidence of systemic autoimmune disease, which is recognized as an underlying disease of APS. She receives a low-dose of aspirin only and have had no recurrence of perniosis so far.
