Abstract
We describe a 49-year-old woman with amicrobial pustulosis associated with autoimmune disease. She had noticed eruptions of the intertriginous folds and scalp beginning 7-8 years earlier. Six months before her admission, she was diagnosed as having systemic lupus erythematosus (SLE). She was admitted to our hospital because the eruption had spread,without any worsening of her SLE symptoms. The eruption, which involved the scalp, reticular folds, flexural and anogenital areas, and the trunk and buttocks, consisted of coalesced pustules forming large, crusting plaques. We started to treat the patient with cimetidine and ascorbic acid, and an improvement was obtained over the course of two weeks. The present case suggests the effectiveness of cimetidine and ascorbic acid treatment as a safe alternative to corticosteroids.
