Abstract
Case 1 : An 8-month-old boy. One month before the first visit to hospital, a bean-size red nodule appeared on his right cheek. Oral antibiotics and topical antifungal ointments were not effective. There had been no episodes of injury to the affected site. Case 2 : A 73-year-old man sustained an injury to his left hand 11 months before the first visit to our hospital. Six months later, a red nodule 3 cm in diameter developed on the left hand dorsa, and after another 2 months, multiple similar red nodules appeared on the right arm, each 2 cm in diameter. Diagnosis of sporotrichosis was made based on histological findings and the isolation of Sporothrix schenckii. Both cases healed following treatment with oral itraconazole and hyperthermia. In contrast to adult cases, there have only been a few case reports of infatile sporotrichosis treated with itraconazole. For the treatment of infantile cases, oral itraconazole is required to be administered at 5 mg/kg/day for 2-3 months.