Abstract
We experienced five cases of leiomyosarcoma (LMS) of the bone, which is a very rare, primary malignant bone tumor. The mean age of the cases was 66 years (49 to 84 years), and they consisted of one male and four females. The affected sites were three distal femora, one proximal tibia, and one distal fibula. The follow-up period ranged from five months to nine years and seven months (mean follow-up period: three years and eleven months).
Two cases were diagnosed with LMS after first biopsy, two cases with giant cell tumor, and one case could not be diagnosed. The two cases diagnosed with LMS after first biopsy showed good prognosis. On the other hand, the three cases not diagnosed LMS had local recurrences, where two cases had bone metastases, and one case had lung metastasis. These cases indicate that good local control can be achieved by resecting the tumor with wide margin. We have to diagnose the tumor as LMS just after biopsy in order to obtain better results and prognosis of LMS of bone.
