Abstract
We experienced two cases of osteomyelitis which needed to be differentiated from bone tumor. These two cases had poor local inflammation signs and systemic inflammation findings. Although they were considered bone tumor on MRI findings, they were diagnosed with osteomyelitis as a result of biopsy. The prognosis of subacute osteomyelitis is comparatively good, but differential diagnosis of malignant bone tumor must be most carefully done. For this reason osteomyelitis should be considered one of the differential diagnosis of bone tumor, and an early biopsy is required when diagnosis is difficult after various examinations.