Abstract
Generally, the reactive arthritis (ReA)is a disease triggered by several infections, such as gram-negative bacteria, including the species Chlamydia, Shigella, and Campylobacter. We reported a case of ReA after rubella and measles vaccination. Six weeks after rubella and measles vaccination was administered, a 17-year-old man presented with pain, acute swelling, and decreasing joint motion of the right hip. He developed a fever of 38°C. Laboratory findings included an erythrocyte sedimentation rate of 54 mm/hour and C-reactive protein (CRP) of 3.88 mg/dl; turbid synovial fluid was aspirated from the joint and contained 5.7×109/l leucocytes. Radiophotographs and MRI did not show any abnormal findings. We suspected septic arthritis of the right hip and performed drainage from the right hip under general anesthesia. After the operation, his joint symptoms subsided, but his fever and CRP kept rising. Up to two days later, his right knee was swollen, all bacterial and viral culture was negative, and human leukocyte antigen B-27 was positive. Her arthritis improved with the administration of nonsteroidal anti-inflammatory drugs. One week later, the knee swelling and pain had settled. This case demonstrates that ReA may occur after rubella and measles vaccination.