Non Familiäre Akroosteolyse

Abstract

A 57 years old housewife appeared at first on January 13, 1974, complaining of deformity of the right toes, ulceration of the right sole, tumor of the right knee, and hypesthesia on burn of the right hand since 29 years old. At the age of 39, ulceration of the right sole and left sole appeared. At the age of 52, amputation of the left lower leg was performed, and deformity of the left toes were appeared. Roentgenogram of the bones were characteristic. They were as follows: 1) osteolysis of the first metatarsal bone 2) osteolysis of the first, second and fifth proximal pharangeal bones. 3) Hypertrophy and deformity of the fifthmetatarsal bone 4) osteophyte of the spine (dorsal vertebra). Sensory disturbance of the lower legs and right forearm were proved, but sensory dissociation were not proved. The results of the routine laboratory tests remained within normal, and leprosy bacillus were not proved.