Experimental Study on Bone and Joint Lesion in Decompression Sickness

Abstract

12 rats were compressed on 5kg/cm² and were allowed to remain at this pressure for 4 hours and then decompressed. This experiment continued for 6 months repeatedly. Histopathological findings showed that occasional necrosis of chondrocytes in the deep layer of the articular cartilage of the humerus and femur were seen. Rough surface of a superficial layer of the articular cartilage were seen. Scattered necrosis of osteocytes in the shaft were found. Necrotic chondrocytes in the deep layer and necrotic osteocytes in the shaft did not show any positive histochemical reaction for LDH, MDH, SDH and NADHDH.