Abstract
A 24-years-old male with hemophilia-A developed a large hemophilic pseudotumor of the right thigh, which was treated by subtrochanteric amputation of the femur. The preoperative level of antihemophilic globulin (A. H. F.) was 0.5%, and clotting time was prolonged over 35 minutes. The dose of 30u/kg of A. H. F. was administered preoperatively and 3 vials were added during operation.
Postoperatively the dose of 30u/kg/day of A. H. F. was given by the method of divided drip infusion three times a day for a week, following by gradual decrease of the doses.
The wound was partially opend twice and healed 10 weeks after the operation.