The Effect of EHDP on the Allogenic Bone Graft in Rats

Kenichiro Shibata; Masao Eguchi; Fumio Wada; Takashi Shimauchi; Tetsu Murao; Shoichi Ikeda; Naoyuki Shibata; Hideya Kawamura; Etsuji Shiota

doi:10.5035/nishiseisai.33.200

Kenichiro Shibata, Masao Eguchi, Fumio Wada, Takashi Shimauchi, Tetsu Murao, Shoichi Ikeda, Naoyuki Shibata, Hideya Kawamura, Etsuji Shiota

Author information

Kenichiro Shibata
Department of Orthopaedic Surgery Faculty of Medicine, Kyushu University
Masao Eguchi
Department of Orthopaedic Surgery Faculty of Medicine, Kyushu University
Fumio Wada
Department of Orthopaedic Surgery Faculty of Medicine, Kyushu University
Takashi Shimauchi
Department of Orthopaedic Surgery Faculty of Medicine, Kyushu University
Tetsu Murao
Department of Orthopaedic Surgery Faculty of Medicine, Kyushu University
Shoichi Ikeda
Department of Orthopaedic Surgery Faculty of Medicine, Kyushu University
Naoyuki Shibata
Department of Orthopaedic Surgery Faculty of Medicine, Kyushu University
Hideya Kawamura
Department of Orthopaedic Surgery Faculty of Medicine, Kyushu University
Etsuji Shiota
[in Japanese]

JOURNAL FREE ACCESS

1984 Volume 33 Issue 1 Pages 200-202

DOI https://doi.org/10.5035/nishiseisai.33.200

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Abstract

The effects of EHDP on the healing process of bone graft in rats tibia were observed roentgenographically and histologically.
In the control and the treatment group with EHDP of 0.5mg/kg/day, remodelling of the callus was found, wheas it was not found in the group with EHDP of 1.0mg/day.
In the groups with EHDP of 5mg/kg/day and 30mg/kg/day, the mineraliztion and calcification of the callus were strongly inhibited.

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