A Case Report of Malignant Fibrous Histiocytoma of Bone

Abstract

We had a case of multiple malignant fibrous histiocytoma of bone (MFH) with no pulmonary metastasis.
It was a fifty-three-year-old female. In her past history, she had had myastenia gravis. She complained of left coxalgia since November, 1983 and bilateral anterior chest pain since March, 1984. In the first radiological examination in May, 1985, we found four radiolucent areas including in the lesser trochanter, the left sixth rib, the right fifth rib and the skull, but no pulmonary metastasis was noted. In histopathological examination, the tumor of the left trochanter was MFH. Between October, 1984 and June, 1985 multiple metastases of bones (bilateral iliums, the right femoral shaft, the right tibial shaft and the right fibulal shaft) and of soft part tissues (the nape, the low back, bilateral upper arms, the right side chest and the right thenar) have be found. The tumors of the nape and the low back examined histopathologically were MFH.
We concluded that it might have had a multicentric synchronous origin because no primary lesion could be determined from the clinical course and affected areas.