Abstract
We examined the effect and assessment of neoadjuvant chemotherapy for 21 spindle cell soft tissue sarcomas treated at our institute from 1982 to 1994. Evaluation of effectiveness of the preoperative chemotherapy was performed by thermogram, 67Ga citrate scintigram, CT scanning and angiogram, and the tumor necrotic rate (≥40%).
The 5-year overall survival rate was 69.3%, and the histological assessment according to the tumor necrotic rate mainly corresponded to the prognosis of these patients in comparison with the graphical assessment. Graphical assessment which agrees with histological assessment may be useful for valuating chemotherapeutic efficacy.