Humoral hypercalcemia of malignancy(HHM）をきたしたPTHrP産生胆嚢癌の1例

井本 佳孝; 六車 直樹; 木村 哲夫; 梶 雅子; 宮本 弘志; 岡村 誠介; 伊東 進; 中園 雅彦; 廣川 満良; 佐野 壽昭

doi:10.11405/nisshoshi.104.401

Case Report

A case of parathyroid hormone-related peptide producing gallbladder carcinoma presenting humoral hypercalcemia of malignancy

Yoshitaka IMOTO, Naoki MUGURUMA, Tetsuo KIMURA, Masako KAJI, Hiroshi MIYAMOTO, Seisuke OKAMURA, Susumu ITO, Masahiko NAKASONO, Mitsuyoshi HIROKAWA, Toshiaki SANO

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JOURNAL FREE ACCESS

2007 Volume 104 Issue 3 Pages 401-406

DOI https://doi.org/10.11405/nisshoshi.104.401

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Abstract

Humoral hypercalcemia of malignancy (HHM) in neoplastic syndrome has been most commonly reported in squamous cell carcinoma. Gallbladder carcinoma with HHM is uncommon. In this report, we describe a male case of gallbladder carcinoma with marked hypercalcemia and a high level of serum parathyroid hormone-related peptide (PTHrP). An immunohistochemical examination using PTHrP was also positive.

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